Aberdeen
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BONE DISEASE
Researchers at the University of Aberdeen are investigating the cause of a flu-like side-effect caused by drugs used to treat osteoporosis. Studies have already led to the discovery of the mechanism behind the side-effect and a potential method for preventing the flu-like illness by using a common anti-lipid drug, statin. With the assistance of an International Pharmaceutical Company a clinical trial is underway in Aberdeen testing whether patients prescribed a statin at the same time as receiving an injection of the osteoporosis drug, bisphosphonate, will have a reduction in the adverse effect profile of the drug. Results from the study are expected to be available late in 2006.
CANCER AND ONCOLOGY RESEARCH
Researchers at the University of Aberdeen are conducting a study of young women under the age of 40 attempting to understand why these women develop breast cancer. The studies focus on the possibility that the natural body systems that protect the cell's own genetic material against damage aren't functioning properly. Aberdeen researchers are trying to understand how certain nutrients can interact with genes in cells and how these effects might be important ion a normal cell changing into a cancer cell. Patients in Aberdeen were one of the first cohorts involved in a study to test a new anti-cancer drug which has now become one of the standard drugs used in the treatment of patients with breast cancer. Patients have also participated in Aberdeen trials to understand the role of new imaging techniques such as Positron Emission Topography and magnetic resonance imaging. These techniques are being examined to understand how they can be used both to diagnose patients with cancer and also how they can be helpful in understanding how patients are responding to treatment. Aberdeen is currently the only location in Scotland with PET; however, facilities will be located in Edinburgh, Glasgow and Dundee in the near future
CARDIOVASCULAR RESEARCH
Researchers at the University of Aberdeen are carrying out a major study which could lead to improved diagnosis and more tailored treatment for heart attack patients. The Chest, Heart, Stroke Scotland and The British Heart Foundation are funding the pioneering research which is using Magnetic Resonance Imaging (MRI) and ultrasound to investigate whether cardiac muscle is alive or dead following a heart attack. Currently, it is difficult to determine if the muscle is dead or alive but not contracting. The research will increase understanding of what happens to the heart muscle following a heart attack and will lead to improved treatment methods for patients.
Key Contact
Dr Gillian C. Auld
Business Development Officer - Translational Medicine
Research & Innovation
University of Aberdeen
Polwarth Building,
Foresterhill,
Aberdeen, AB25 2ZD
Tel: +44 (0) 1224 559699
Fax: +44 (0) 1224 550708
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